4-Methylumbelliferyl phosphate

4-Methylumbelliferyl phosphate

• CAS Number: 3368-04-5
• UNSPSC Description: 4-Methylumbelliferyl phosphate (4-MUP), an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate is also a nerve agent simulant[1][2][3].
• Target Antigen: Phosphatase
• Type: Dye Reagents
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Neuroscience-Neuromodulation
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/4-Methylumbelliferyl_phosphate.html
• Purity: 99.96
• Solubility: H2O : 17.5 mg/mL (ultrasonic)
• Smiles: O=C1C=C(C)C2=CC=C(OP(O)(O)=O)C=C2O1
• Molecular Weight: 256.15
• References & Citations: [1]Chambers JP, et al. Determination of serum acid phosphatase in Gaucher's disease using 4-methylumbelliferyl phosphate. Clin Chim Acta. 1977 Oct 1;80(1):67-77.|[2]Watanabe F, et al. The analysis of alkaline phosphatase isoenzyme using 4-methylumbelliferyl phosphate as substrate on a cellulose acetate membrane. Clin Chim Acta. 1979 Feb 1;91(3):273-6.|[3]Hao Chen, et al. Autonomic Molecular Transport for Ultrasensitive Surface-Enhanced Infrared Absorption Spectroscopy. ACS Appl. Polym. Mater. 2020, 2, 9, 3929-3935
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, protect from light)
• Clinical Information: No Development Reported