SingleFlowEx CD36 APC

• Description:

  SingleFlowEx is fluorochrome-labeled monoclonal antibody single reagent for use in laboratory-developed multicolor flow cytometry tests in order to examine human clinical samples. SingleFlowEx can be used in various multicolor combinations. Laboratory shall establish the SingleFlowEx performance characteristics in conjunction with other reagents in normal and pathological samples.

• Certification:

  RUO (GMP)

• Clone:

  CB38

• Applications:

  FC (QC tested)

• Concentration:

  0.040 mg/mL

• Format:

  APC

• Buffer:

  Stabilizing MES buffered saline, pH 5.5, 15 mM sodium azide

• References & Citations:

  *Kapinsky M, Torzewski M, Büchler C, Duong CQ, Rothe G, Schmitz G: Enzymatically degraded LDL preferentially binds to CD14 (high) CD16 (+) monocytes and induces foam cell formation mediated only in part by the class B scavenger-receptor CD36. Arterioscler Thromb Vasc Biol. 2001 Jun;21 (6) :1004-10., URL: https://www.ncbi.nlm.nih.gov/pubmed/11397711, *McKenna RW, Washington LT, Aquino DB, Picker LJ, Kroft SH: Immunophenotypic analysis of hematogones (B-lymphocyte precursors) in 662 consecutive bone marrow specimens by 4-color flow cytometry. Blood. 2001 Oct 15;98 (8) :2498-507., URL: https://www.ncbi.nlm.nih.gov/pubmed/11588048, *Moniuszko M, Kowal K, Rusak M, Pietruczuk M, Dabrowska M, Bodzenta-Lukaszyk A: Monocyte CD163 and CD36 expression in human whole blood and isolated mononuclear cell samples: influence of different anticoagulants. Clin Vaccine Immunol. 2006 Jun;13 (6) :704-7., URL: https://www.ncbi.nlm.nih.gov/pubmed/16760331, *Leukocyte Typing IV., Knapp W. et al. (Eds.), Oxford University Press (1989) ., URL: , *Alessio M, Ghigo D, Garbarino G, Geuna M, Malavasi F: Analysis of the human CD36 leucocyte differentiation antigen by means of the monoclonal antibody NL07. Cell Immunol. 1991 Oct 15;137 (2) :487-500., URL: https://www.ncbi.nlm.nih.gov/pubmed/1716523, *Alessio M, Roggero S, Bussolino F, Saitta M, Malavasi F: Characterization of the murine monoclonal antibody NL07 specific for the human thrombospondin receptor (CD36 molecule) . Curr Stud Hematol Blood Transfus. 1991; (58) :182-6., URL: https://www.ncbi.nlm.nih.gov/pubmed/1720081, *Alessio M, Greco NJ, Primo L, Ghigo D, Bosia A, Tandon NN, Ockenhouse CF, Jamieson GA, Malavasi F: Platelet activation and inhibition of malarial cytoadherence by the anti-CD36 IgM monoclonal antibody NL07. Blood. 1993 Dec 15;82 (12) :3637-47., URL: https://www.ncbi.nlm.nih.gov/pubmed/7505121, *Fadok VA, Warner ML, Bratton DL, Henson PM: CD36 is required for phagocytosis of apoptotic cells by human macrophages that use either a phosphatidylserine receptor or the vitronectin receptor (alpha v beta 3) . J Immunol. 1998 Dec 1;161 (11) :6250-7., URL: https://www.ncbi.nlm.nih.gov/pubmed/9834113, *Matasić R, Dietz AB, Vuk-Pavlović S: Dexamethasone inhibits dendritic cell maturation by redirecting differentiation of a subset of cells. J Leukoc Biol. 1999 Dec;66 (6) :909-14., URL: https://www.ncbi.nlm.nih.gov/pubmed/10614771, *Hoffmann PR, deCathelineau AM, Ogden CA, Leverrier Y, Bratton DL, Daleke DL, Ridley AJ, Fadok VA, Henson PM: Phosphatidylserine (PS) induces PS receptor-mediated macropinocytosis and promotes clearance of apoptotic cells. J Cell Biol. 2001 Nov 12;155 (4) :649-59. , URL: https://www.ncbi.nlm.nih.gov/pubmed/11706053, *Use of this product has not been published., URL:

• Other References:

  *Gaillard D, Laugerette F, Darcel N, El-Yassimi A, Passilly-Degrace P, Hichami A, Akhtar Khan N, Montmayeur JP, Besnard P: The gustatory pathway is involved in CD36-mediated orosensory perception of long-chain fatty acids in the mouse. FASEB J. 2007 Dec 27, URL: https://www.ncbi.nlm.nih.gov/pubmed/18162488?ordin, *van Oort MM, van Doorn JM, Bonen A, Glatz JF, van der Horst DJ, Rodenburg KW, Luiken JJ: Insulin-induced translocation of CD36 to the plasma membrane is reversible and shows similarity to that of GLUT4. Biochim Biophys Acta. 2007 Dec 15, URL: https://www.ncbi.nlm.nih.gov/pubmed/18167317?ordin, *Won WJ, Bachmann MF, Kearney JF: CD36 Is Differentially Expressed on B Cell Subsets during Development and in Responses to Antigen. J Immunol. 2008 Jan 1;180 (1) :230-7., URL: https://www.ncbi.nlm.nih.gov/pubmed/18097024?ordin

• Storage Conditions:

  Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.