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LY2048978

CAT: 0804-HY-118615Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-118615Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LY2048978 is a non-selective opioid receptor antagonist with Ki of 0.287, 0.471 and 1.05 nM for human mu, kappa and delta opioid receptors in vitro, respectively. LY2048978 can be used in the research of major depressive disorder and alcohol use disorder[1].
CAS Number
676495-11-7
UNSPSC
12352005
Target
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ly2048978.html
Smiles
O=C(C1=CC=C(C=C1)OC2=CC=C(C=C2)CNCCCCC)N
Molecular Formula
C19H24N2O2
Molecular Weight
312.41
References & Citations
[1]Rorick-Kehn L M, et al. LY2456302 is a novel, potent, orally-bioavailable small molecule kappa-selective antagonist with activity in animal models predictive of efficacy in mood and addictive disorders[J]. Neuropharmacology, 2014, 77: 131-144.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
δ Opioid Receptor/DOR; κ Opioid Receptor/KOR; μ Opioid Receptor/MOR

Alternative Products

CatalogName
MBS5774172LY2048978

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