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Fasoracetam

CAT: 0804-HY-107481-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-107481-01Size:5 mg
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Description
Fasoracetam (NS 105) is the activator of metabotropic glutamate receptor (mGluR) . Fasoracetam (NS 105) has the potential for the research of attention-deficit hyperactivity disorder (ADHD) and Alzheimer's disease (AD) [1][2].
CAS Number
110958-19-5
Product Name Alternative
NS 105
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/fasoracetam.html
Purity
99.41
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C([C@@H]1NC(CC1)=O)N2CCCCC2
Molecular Formula
C10H16N2O2
Molecular Weight
196.25
Precautions
H302, H315, H319, H335
References & Citations
[1]Elia J, et al. Fasoracetam in adolescents with ADHD and glutamatergic gene network variants disrupting mGluR neurotransmitter signaling. Nat Commun. 2018;9 (1) :4.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3

Chemical Information

Fasoracetam

Fasoracetam is an amino acid amide.

CAS Number110958-19-5
PubChem CID198695
IUPAC Name(5R)-5-(piperidine-1-carbonyl)pyrrolidin-2-one
Molecular FormulaC10H16N2O2
Molecular Weight196.25
XLogP0
Topological Polar Surface Area49.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Heavy Atom Count14
Formal Charge0
Complexity247
SMILES
C1CCN(CC1)C(=O)[C@H]2CCC(=O)N2
InChI
InChI=1S/C10H16N2O2/c13-9-5-4-8(11-9)10(14)12-6-2-1-3-7-12/h8H,1-7H2,(H,11,13)/t8-/m1/s1
InChIKey
GOWRRBABHQUJMX-MRVPVSSYSA-N
Chemical Structure
2D Structure
2D structure of Fasoracetam
CAS: 110958-19-5
CID: 198695
Formula: C10H16N2O2
MW: 196.25
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight196.25
XLogP30
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass196.121177757
Monoisotopic Mass196.121177757
Topological Polar Surface Area49.4 Ų
Heavy Atom Count14
Formal Charge0
Complexity247
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes