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Tildacerfont

CAT: 0804-HY-113603-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-113603-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tildacerfont is a potent and orally active corticotrophin-releasing factor type 1 (CRF1) receptort antagonis. Tildacerfont effectively reduces adrenocorticotropic hormone (ACTH) and adrenal androgen levels. Tildacerfont has favourable safety profile. Tildacerfont can be used for researching congenital adrenal hyperplasia[1].
CAS Number
1014983-00-6
Product Name Alternative
SPR001; LY2371712
UNSPSC
12352005
Target
CRFR
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tildacerfont.html
Purity
98.60
Solubility
DMSO : 10 mg/mL (ultrasonic)
Smiles
CCC(CC)C1=CC(C)=NC2=C(C(C)=NN12)C3=C(N=C(S3)N4CCOCC4)Cl
Molecular Formula
C20H26ClN5OS
Molecular Weight
419.97
References & Citations
[1]Prete A, et al. Clinical advances in the pharmacotherapy of congenital adrenal hyperplasia. Eur J Endocrinol. 2021;186 (1) :R1-R14. Published 2021 Nov 30.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
CRFR1

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