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Clemastanin B

CAT: 0804-HY-N6025-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N6025-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Clemastanin B, a lignin, has potent anti-influenza activities by inhibiting the virus multiplication, prophylaxsis and blocking the virus attachment. Clemastanin B targets viral endocytosis, uncoating or ribonucleoprotein (RNP) export from the nucleus. Clemastanin B has antioxidant and anti-inflammatory activities[1][2][3].
CAS Number
112747-98-5
UNSPSC
12352005
Target
Influenza Virus
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/clemastanin-b.html
Purity
99.71
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
OC[C@@H]1[C@](C2=CC(OC)=C(C=C2)O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)([H])OC[C@@H]1CC4=CC(OC)=C(C=C4)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)CO
Molecular Formula
C32H44O16
Molecular Weight
684.68
References & Citations
[1]Zifeng Yang, et al. Antiviral activity of Isatis indigotica root-derived clemastanin B against human and avian influenza A and B viruses in vitro. Int J Mol Med. 2013 Apr;31 (4) :867-73.|[2]Ping Xiao, et al. Antiviral activities against influenza virus (FM1) of bioactive fractions and representative compounds extracted from Banlangen (Radix Isatidis) . J Tradit Chin Med. 2016 Jun;36 (3) :369-76.|[3]Ping Xiao, et al. In vitro antioxidant and anti-inflammatory activities of Radix Isatidis extract and bioaccessibility of six bioactive compounds after simulated gastro-intestinal digestion. J Ethnopharmacol. 2014 Nov 18;157:55-61.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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