Palmitoyl Tetrapeptide-3

Palmitoyl Tetrapeptide-3

• CAS Number: 221227-05-0
• UNSPSC Description: Palmitoyl Tetrapeptide-3 (Palmitoyl Tetrapeptide-7) is a synthetic peptide corresponding to amino acids 341-344 of the human immunoglobulin heavy chain, with the ability to stimulate phagocytosis. Palmitoyl tetrapeptide-3 reduces interleukin-6 (IL-6) secretion in keratinocytes and inhibits the UVB radiation-exposure inflammatory response of skin. Palmitoyl tetrapeptide-3 It also has anti-inflammatory and anti-aging effects, reducing skin wrinkles by promoting the production of elastic fibers in the papillary dermis[1][2][3][4].
• Target Antigen: Interleukin Related
• Type: Peptides
• Related Pathways: Immunology/Inflammation
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/palmitoyl-tetrapeptide-3.html
• Purity: 99.20
• Solubility: DMF : 10 mg/mL (ultrasonic;adjust pH to 3 with HCl)|H2O : < 0.1 mg/mL (ultrasonic)
• Smiles: N=C(N)NCCC[C@@H](C(O)=O)NC([C@H]1N(C([C@H](CCC(N)=O)NC(CNC(CCCCCCCCCCCCCCC)=O)=O)=O)CCC1)=O
• Molecular Weight: 694.91
• References & Citations: [1]Rocchi R, et al. Synthesis and biological activity of tuftsin and rigin derivatives containing monosaccharides or monosaccharide derivatives. Int J Pept Protein Res. 1987 Feb;29(2):262-75.|[2]Schagen S K. Topical peptide treatments with effective anti-aging results[J]. Cosmetics, 2017, 4(2): 16.|[3]Mondon P, et al. Evaluation of dermal extracellular matrix and epidermal–dermal junction modifications using matrix‐assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications[J]. Journal of cosmetic dermatology, 2015, 14(2): 152-160.|[4]Fengzhu Li, et al. Clinical evidence of the efficacy and safety of a new multi-peptide anti-aging topical eye serum. J Cosmet Dermatol. 2023 Dec;22(12):3340-3346.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported