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(-) -Halofantrine

CAT: 0804-HY-A0148BSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-A0148BSize:1 Each
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Description
(-) -Halofantrine ((-) -SKF-102886 free base; (-) -WR-171669) is an inhibitor of the malignant malaria parasite (P. falciparum) and targets multidrug-resistant P. falciparum. The pharmacokinetic parameters of (-) -Halofantrine in rats vary depending on the route of administration, distinguishing it from other isomers[1].
CAS Number
66051-76-1
Product Name Alternative
(-) -SKF-102886 (free base) ; (-) -WR-171669
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/minus-halofantrine.html
Smiles
OC(CCN(CCCC)CCCC)C1=CC2=C(Cl)C=C(Cl)C=C2C3=CC(C(F)(F)F)=CC=C31.[Rotation(-)]
Molecular Formula
C26H30Cl2F3NO
Molecular Weight
500.42
References & Citations
[1]Brocks DR, et al. Pharmacokinetics of halofantrine in the rat: stereoselectivity and interspecies comparisons. Biopharm Drug Dispos. 1999 Apr;20 (3) :165-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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