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CCT369260

CAT: 0804-HY-129188-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-129188-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CCT369260 (compound 1), a chemical probe, is an orally avtive B-cell lymphoma 6 (BCL6) inhibitor with anti-tumor activity. CCT369260 (compound 1) exhibits an IC50 of 520 nM[1].
CAS Number
2647503-57-7
UNSPSC
12352005
Target
Bcl-2 Family; Molecular Glues
Type
Reference compound
Related Pathways
Apoptosis; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bcl6-in-3.html
Purity
99.67
Solubility
DMSO : 300 mg/mL (ultrasonic)
Smiles
O=C1N(CCC(C)(O)C)C2=CC(NC3=NC(N4C[C@@H](C)C(F)(F)[C@@H](C)C4)=NC=C3Cl)=CC=C2N1C
Molecular Formula
C24H31ClF2N6O2
Molecular Weight
508.99
References & Citations
[1]Benjamin R Bellenie, et al. Achieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders. J Med Chem. 2020 Apr 23;63 (8) :4047-4068.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T63503-01CCT369260

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