Cyclooxygenase 1, sheep

• UNSPSC Description:

  Cyclooxygenase 1, sheep (COX-1) is a 71 kDa membrane bound protein predominantly present in endoplasmic reticulum. Cyclooxygenase 1 has three domains, the epidermal growth factor (EGF) like domain, enzymatic and membrane binding domain. Cyclooxygenase 1 mediates prostaglandin synthesis and is modulated by anti-inflammatory nonsteroidal drugs[1].

• Target Antigen:

  Endogenous Metabolite

• Type:

  Enzyme

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/cyclooxygenase-1-sheep.html

• Solubility:

  10 mM in DMSO

• Smiles:

  [Cyclooxygenase 1, sheep]

• References & Citations:

  [1]Katrina M Mirabito Colafella, et al. Aspirin for the prevention and treatment of pre-eclampsia: A matter of COX-1 and/or COX-2 inhibition? Basic Clin Pharmacol Toxicol. 2020 Aug;127(2):132-141.

• Shipping Conditions:

  Dry Ice

• Storage Conditions:

  Store at -80°C for 2 years

• Clinical Information:

  No Development Reported

• CAS Number:

  329967-85-3