Pim1/AKK1-IN-1

Pim1/AKK1-IN-1

• CAS Number: 1093222-27-5
• UNSPSC Description: Pim1/AKK1-IN-1 is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and also inhibits MPSK1 and TNIK.
• Target Antigen: Pim
• Type: Reference compound
• Related Pathways: JAK/STAT Signaling
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/Pim1-AKK1-IN-1.html
• Purity: 98.40
• Solubility: DMSO : 50 mg/mL (ultrasonic)
• Smiles: N#CC1=CC=C(C2=CN=C3C(C(NC(C4=CC=CN=C4)=O)=CN3)=C2)C=C1
• Molecular Weight: 339.35
• References & Citations: [1]Bamborough P, et al. Assessment of chemical coverage of kinome space and its implications for kinase drug discovery. J Med Chem. 2008 Dec 25;51(24):7898-914.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported