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Antipyrine

CAT: 0804-HY-B0171-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0171-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Antipyrine (Phenazone) is an orally active antipyretic and analgesic. Antipyrine can be used as a probe agent for oxidative agent metabolism. Antipyrine also delays gastric emptying (GE) in rats[1][2][3][4].
CAS Number
60-80-0
Product Name Alternative
Phenazone; Phenazon
UNSPSC
12352005
Hazard Statement
H302
Target
Fluorescent Dye; GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Applications
COVID-19-immunoregulation
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Antipyrine.html
Purity
99.98
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL
Smiles
O=C1N(C2=CC=CC=C2)N(C)C(C)=C1
Molecular Formula
C11H12N2O
Molecular Weight
188.23
Precautions
H302
References & Citations
[1]Stevenson, I.H., Factors influencing antipyrine elimination. Br J Clin Pharmacol, 1977. 4 (3) : p. 261-5.|[2]Engel G, et, al. Antipyrine as a probe for human oxidative drug metabolism: identification of the cytochrome P450 enzymes catalyzing 4-hydroxyantipyrine, 3-hydroxymethylantipyrine, and norantipyrine formation. Clin Pharmacol Ther. 1996 Jun;59 (6) :613-23.|[3]RENKIN EM. Capillary and cellular permeability to some compounds related to antipyrine. Am J Physiol. 1953 Apr;173 (1) :125-30.|[4]Soares AC, et al. Effect of antipyrine on the gastric emptying of liquid in rats. Braz J Med Biol Res. 2006 Nov;39 (11) :1507-12.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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