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Pyr3

CAT: 0804-HY-108465-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-108465-01Size:5 mg
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Description
Pyr3 is a selective inhibitor of transient receptor potential canonical channel 3 (TRPC3), with an IC50 of 700 nM for TRPC3-mediated Ca2+ influx.
CAS Number
1160514-60-2
UNSPSC
12352005
Hazard Statement
H302, H314
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Pyr3.html
Concentration
10mM
Purity
99.90
Solubility
DMSO : ≥ 125 mg/mL
Smiles
O=C(C1=C(C(F)(F)F)N(C2=CC=C(NC(/C(Cl)=C(Cl)/Cl)=O)C=C2)N=C1)OCC
Molecular Formula
C16H11Cl3F3N3O3
Molecular Weight
456.63
Precautions
H302, H314
References & Citations
[1]Kiyonaka S, et al. Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound. Proc Natl Acad Sci U S A. 2009 Mar 31;106 (13) :5400-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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