Podofilox (Standard)

• Description :

  Podofilox (Standard) is the analytical standard of Podofilox. This product is intended for research and analytical applications. Podofilox (Podophyllotoxin) is a potent inhibitor of microtubule assembly and DNA topoisomerase II.

• CAS Number :

  [518-28-5]

• Product Name Alternative :

  Podophyllotoxin (Standard)

• UNSPSC :

  12352005

• Target :

  Microtubule/Tubulin; Reference Standards

• Type :

  Reference Standards

• Related Pathways :

  Cell Cycle/DNA Damage; Cytoskeleton; Others

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/podofilox-standard.html

• Smiles :

  O=C1OC[C@]2([H])[C@@H](O)C3=C(C=C4OCOC4=C3)[C@@H](C5=CC(OC)=C(OC)C(OC)=C5)[C@]21[H]

• Molecular Formula :

  C22H22O8

• Molecular Weight :

  414.41

• References & Citations :

  [1]Wang B, Chen L, Zhen H, et al. Proteomic changes induced by podophyllotoxin in human cervical carcinoma HeLa cells. Am J Chin Med. 2013;41 (1) :163-75.|[2]Guerrero E, Abad A, Montenegro G, et al. Analgesic and anti-inflammatory activity of podophyllotoxin derivatives. Pharm Biol. 2013 Jan 31.|[3]Li M, Zhou L, Yang D, et al. Biochemical composition and antioxidant capacity of extracts from Podophyllum hexandrum rhizome. BMC Complement Altern Med. 2012 Dec 22;12:263.|[4]Prasad V, Chaudhuri AR, Curcio M, et al. Podophyllotoxin and nocodazole counter the effect of IKP104 on tubulin decay. J Protein Chem. 1998 Oct;17 (7) :663-8.|[5]Podophyllotoxin

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards