Products for Research Use Only

RUNX1/AML1 Rabbit Polyclonal Antibody

CAT: 0013-GTR17691341Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR17691341Size:100 µg
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Description
RUNX1/AML1 Rabbit Polyclonal Antibody
Product Name Alternative
Runt-related transcription factor 1; Acute myeloid leukemia 1 protein; Core-binding factor subunit alpha-2; CBF-alpha-2; Oncogene AML-1; Polyomavirus enhancer-binding protein 2 alpha B subunit; PEA2-alpha B; PEBP2-alpha B; SL3-3 enhancer factor 1 alpha B subunit; SL3/AKV core-binding factor alpha B subunit; RUNX1; AML1, CBFA2
UniProt
Q01196
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human RUNX1, identical to the related mouse and rat sequences.
Target
Runt-related transcription factor 1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cancer Biology, Epigenetics & Chromatin, Neuroscience, Stem Cell & Developmental Biology
Purification
Immunogen affinity purified.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Dilution
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat Immunohistochemistry (Frozen Section), 0.5-1μg/ml, Rat
Form
Lyophilized
Molecular Weight
55 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
IHC, IHC-Fr, WB
Host or Source
Rabbit
Preservative
Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg NaN3. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
Isotype
Rabbit IgG

UniProtKB · Q01196

Runt-related transcription factor 1

RUNX1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q01196
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RUNX1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8MV94, B2RMS4, D3DSG1, O60472, O60473, O76047, O76089, Q13081, Q13755, Q13756, Q13757, Q13758, Q13759, Q15341, Q15343, Q16122, Q16284, Q16285, Q16286, Q16346, Q16347, Q92479
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationMethylationPhosphoprotein

Molecular function

ActivatorDNA-bindingRepressor

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Ligand

Chloride

Disease

Disease variantProto-oncogene

Cellular component

Nucleus

Biological process

TranscriptionTranscription regulation