Products for Research Use Only

GSDMD-N Rabbit Polyclonal Antibody

CAT: 0013-GTR18399359-01Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18399359-01Size:50 µg
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Description
GSDMD-N Rabbit Polyclonal Antibody
Product Name Alternative
Gasdermin-D|Gasdermin domain-containing protein 1|Gasdermin-D, N-terminal (GSDMD-NT, hGSDMD-NTD) |Gasdermin-D, p13|Gasdermin-D, 13 kDa (13 kDa GSDMD) |Gasdermin-D, p40|GSDMD|DFNA5L|GSDMDC1
UniProt
P57764
Reactivity
Human, Mouse
Immunogen
Gasdermin D
Target
GSDMD-N
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50-53 kDa
References & Citations
Ying Gao et al. Xue-Jie-San alleviates Crohn's disease through suppressing endothelial cell pyroptosis via the TLR4/NF-κB/NLRP3 pathway J Ethnopharmacol, (2026), Junkai Xu et al. Dexmedetomidine potentiates cisplatin chemosensitivity in esophageal carcinoma cells via the SREBF1/miR-185-5p/Caspase-1 axis through pyroptosis Int Immunopharmacol ., (2026), Lixiang Fang 1, Zhenfei Yu 2, Xiaoling Qian 2, Huiqin Fang 1, Yakun Wang LDHA exacerbates myocardial ischemia-reperfusion injury through inducing NLRP3 lactylation BMC Cardiovasc Disord ., (2024), Dandan Chi 1, Feng Li 2, Zhimin Wang 3 Mechanisms of methyltransferase-like 3-mediated microglial pyroptosis in sepsis-associated encephalopathy Neuroreport, (2025)
Pubmed id
41936260, 41966778, 39548367, 41025575
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ELISA, WB
Host or Source
Rabbit
Isotype
IgG

UniProtKB · P57764

Gasdermin-D

GSDMD_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P57764
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GSDMD
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K702, D3DWJ9, Q96Q98
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Cellular component

Cell membraneCytoplasmInflammasomeMembraneMitochondrionNucleusSecreted

PTM

GlycoproteinIsopeptide bondLipoproteinPalmitatePhosphoproteinUbl conjugation

Biological process

ImmunityInflammatory responseInnate immunityNecrosisTranscriptionTranscription regulation

Ligand

Lipid-binding

Domain

TransmembraneTransmembrane beta strand