Products for Research Use Only
RegisterLogin

VSPPLTLGQLLS

CAT: 0804-HY-P3695-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P3695-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
VSPPLTLGQLLS is a small peptide FGFR3 inhibitor, peptide P3, inhibits FGFR3 phosphorylation. VSPPLTLGQLLS inhibits 9-cisRA-induced tracheal lymphangiogenesis and blocks lymphatic endothelial cell (LEC) proliferation, migration, and tubule formation[1][2].
CAS Number
1206896-24-3
UNSPSC
12352209
Target
FGFR
Type
Peptides
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vsppltlgqlls.html
Purity
98.81
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
OC[C@@H](C(O)=O)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCC(N)=O)NC(CNC([C@H](CC(C)C)NC([C@H]([C@H](O)C)NC([C@H](CC(C)C)NC([C@H]1N(C([C@H]2N(C([C@H](CO)NC([C@H](C(C)C)N)=O)=O)CCC2)=O)CCC1)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C56H97N13O17
Molecular Weight
1224.45
References & Citations
[1]Perrault DP, et al. Small Peptide Modulation of Fibroblast Growth Factor Receptor 3-Dependent Postnatal Lymphangiogenesis. Lymphat Res Biol. 2019 Feb;17 (1) :19-29. |[2]Jin M, et al. A novel FGFR3-binding peptide inhibits FGFR3 signaling and reverses the lethal phenotype of mice mimicking human thanatophoric dysplasia. Hum Mol Genet. 2012 Dec 15;21 (26) :5443-55.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported

Alternative Products

CatalogName
BA8950-10VSPPLTLGQLLS
A22997-1VSPPLTLGQLLS 1mg
T76368-01VSPPLTLGQLLS TFA
A22997-10VSPPLTLGQLLS 10mg
A22997-5VSPPLTLGQLLS 5mg

Popular Products