Flt1 Protein, Active

• Description:

  Flt1 Protein, Active_x000D_ Catalog number: B2019377_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 5  µg_x000D_ Molecular Weight or Concentration: 89 kDa_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: ˆ’70°C_x000D_ Keywords: Flt1 Protein, Active_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Yang X, Zhao Y, Wei Q, Zhu X, Wang L, Zhang W, Liu X, Kuai J, Wang F, Wei W. GRK2 inhibits Flt-1(+) macrophage infiltration and its proangiogenic properties in rheumatoid arthritis Acta Pharm Sin B. 2024 Jan;14(1):241-255._x000D_ 2: Pradhan A, Che L, Ustiyan V, Reza AA, Pek NM, Zhang Y, Alber AB, Kalin TR, Wambach JA, Gu M, Kotton DN, Siefert ME, Ziady AG, Kalin TV, Kalinichenko VV. Novel FOXF1-Stabilizing Compound TanFe Stimulates Lung Angiogenesis in Alveolar Capillary Dysplasia Am J Respir Crit Care Med. 2023 Apr 15;207(8):1042-1054._x000D_ 3: Akiyama T, Sadahiro T, Yamada Y, Fujita R, Abe Y, Nakano K, Honda S, Ema M, Kubota Y, Sakai S, Hizawa N, Ieda M. Flk1 Deficiency and Hypoxia Synergistically Promote Endothelial Dysfunction, Vascular Remodeling, and Pulmonary Hypertension Arterioscler Thromb Vasc Biol. 2023 Sep;43(9):1668-1683._x000D_ 4: Raikwar NS, Liu KZ, Thomas CP. Protein kinase C regulates FLT1 abundance and stimulates its cleavage in vascular endothelial cells with the release of a soluble PlGF/VEGF antagonist Exp Cell Res. 2013 Oct 15;319(17):2578-87._x000D_ 5: Geifman-Holtzman O, Xiong Y, Holtzman EJ. Gadd45 stress sensors in preeclampsia Adv Exp Med Biol. 2013;793:121-9._x000D_ 6: Jiangxue H, Liling Y, Fang X, Shumei Y, Gengying L, Xuejun R, Yao Y, Chuan N, Jie Y, Zhuxiao R. Wnt5a-Flt1 activation contributes to preterm altered cerebral angiogenesis after prenatal inflammation Pediatr Neonatol. 2023 Sep;64(5):528-537._x000D_ 7: Wang Q, Xu B, Du J, Xu X, Shang C, Wang X, Wang J. MicroRNA-139-5p/Flt1/Wnt/β-catenin regulatory crosstalk modulates the progression of glioma Int J Mol Med. 2018 Apr;41(4):2139-2149._x000D_ 8: Zachary I. Vascular endothelial growth factor Int J Biochem Cell Biol. 1998 Nov;30(11):1169-74._x000D_ 9: Shibuya M. [VEGF-receptor inhibitors for anti-angiogenesis] Nihon Yakurigaku Zasshi. 2003 Dec;122(6):498-503._x000D_ 10: Kliche S, Waltenberger J. VEGF receptor signaling and endothelial function IUBMB Life. 2001 Jul;52(1-2):61-6. _x000D_ _x000D_ Products Related to Flt1 Protein, Active can be found at Proteins

• Short Description:

  Catalog Number: B2019377 (5  µg)_x000D_ Flt1, also known as Vascular Endothelial Growth Factor Receptor 1 (VEGFR-1), is a protein crucial for regulating angiogenesis, the formation of new blood vessels. It binds to VEGF, influencing endothelial cell processes. Flt1 is a receptor tyrosine kinase with an active form when bound to VEGF, playing a significant role in normal physiology and various diseases. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5