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Ranatensin

CAT: 0804-HY-P1685Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P1685Size:1 Each
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Description
Ranatensin is a undecapeptide and a Bombesin Receptor angonist, can be isolated from amphibian skin, such as the frog, Rana pipiens. Ranatensin could maintain the dynamic balance of animal blood pressure, without cross-tachyphylaxis with Angiotensin amide , Bradykinin (HY-P0206), or Norepinephrine (HY-13715)[2].
CAS Number
29451-71-6
UNSPSC
12352209
Target
Bombesin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ranatensin.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1N(CCC1)C([C@H](C(C)C)NC([C@H]2NC(CC2)=O)=O)=O)N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@@H](C)C(N[C@@H](C(C)C)C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CCSC)=O)CC3=CC=CC=C3)=O)CC4=CN=CN4)=O)=O)=O)=O)CC5=CNC6=CC=CC=C56)=O
Molecular Formula
C61H84N16O13S
Molecular Weight
1281.48
References & Citations
[1]Geller RG, et al. The action of ranatensin, a new polypeptide from amphibian skin, on the blood pressure of experimental animals. Br J Pharmacol. 1970 Dec;40 (4) :605-16. |[2]Jensen RT, et al. A synthetic peptide that is a bombesin receptor antagonist. Nature. 1984 May 3-9;309 (5963) :61-3.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported