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IgD

CAT: 0013-GTR18398437-01Size: 0.1 mLDry Ice: NoHazardous: No
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CAT#:0013-GTR18398437-01Size:0.1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IgD antibody validated for immunohistochemistry on 76 different Normal Tissues
Product Name Alternative
Pivotal molecule in the immune response
UniProt
P01880
Reactivity
Human
Immunogen
Recombinant human IGHD fragment
Clonality
Monoclonal
Clone
MSVA-701R
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Dilution
1:100-1:200
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Positive Control: Tonsil: A strong IgD staining should be seen in lymphocytes of the mantle zone. Negative Control: Tonsil: Epithelial cells and most “non-mantle zone” lymphocytes should not stain for IgD. Cellular Localization: Cytoplasmic Protocol Recommendations: Manual Protocol: Freshly cut sections should be used (less than 10 days between cutting and staining) . Heat-induced antigen retrieval for 5 minutes in an autoclave at 121°C in pH 7.8 Target Retrieval Solution buffer. Apply the antibody at a dilution of 1:150 at 37°C for 60 minutes. Visualization of bound antibody by the EnVision Kit (Dako, Agilent) according to the manufacturer’s directions.
Tested Applications
IHC
Host or Source
Rabbit
Isotype
IgG

UniProtKB · P01880

Immunoglobulin heavy constant delta

IGHD_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01880
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IGHD
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A0A087WUS7, Q6P4I8, Q8WU38
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Adaptive immunityImmunity

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneImmunoglobulinMembraneSecreted

PTM

Disulfide bondGlycoprotein

Domain

Immunoglobulin domainTransmembraneTransmembrane helix

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