Paraxanthine

• Description:

  Paraxanthine, a caffeine metabolite, provides protection against Dopaminergic cell death via stimulation of Ryanodine Receptor Channels.

• UNSPSC:

  12352005

• Hazard Statement:

  H302

• Target:

  Drug Metabolite; Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/Paraxanthine.html

• Purity:

  99.97

• Solubility:

  DMSO : 25 mg/mL (ultrasonic; warming; heat to 70°C)

• Smiles:

  O=C (N1C) NC2=C (N (C) C=N2) C1=O

• Molecular Formula:

  C7H8N4O2

• Molecular Weight:

  180.17

• Precautions:

  H302

• References & Citations:

  [1]Guerreiro S, et al. Paraxanthine, the primary metabolite of caffeine, provides protection against dopaminergic cell death via stimulation of ryanodine receptor channels. Mol Pharmacol. 2008 Oct;74 (4) :980-9.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  Phase 2

• Isoform:

  Human Endogenous Metabolite; Microbial Metabolite

• CAS Number:

  611-59-6