Paraxanthine

• Description :

  Paraxanthine, a caffeine metabolite, provides protection against Dopaminergic cell death via stimulation of Ryanodine Receptor Channels.

• UNSPSC :

  12352005

• Hazard Statement :

  H302

• Target :

  Drug Metabolite; Endogenous Metabolite

• Type :

  Natural Products

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/Paraxanthine.html

• Purity :

  99.97

• Solubility :

  DMSO : 25 mg/mL (ultrasonic; warming; heat to 70°C)

• Smiles :

  O=C(N1C)NC2=C(N(C)C=N2)C1=O

• Molecular Formula :

  C7H8N4O2

• Molecular Weight :

  180.17

• Precautions :

  H302

• References & Citations :

  [1]Guerreiro S, et al. Paraxanthine, the primary metabolite of caffeine, provides protection against dopaminergic cell death via stimulation of ryanodine receptor channels. Mol Pharmacol. 2008 Oct;74 (4) :980-9.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  Phase 2

• Isoform :

  Human Endogenous Metabolite; Microbial Metabolite

• CAS Number :

  [611-59-6]