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MMV667492

CAT: 0804-HY-124144Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-124144Size:1 Each
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Description
MMV667492 is a potent Ezrin inhibitor with the activity to inhibit the invasion phenotype of osteosarcoma cells. MMV667492 exhibited potent anti-Ezrin activity in all biological assays and its compound properties were superior to NSC305787. MMV667492 was able to exhibit morphological defect phenotypes associated with Ezrin inhibition in zebrafish embryos. MMV667492 also showed the ability to inhibit the lung metastasis of osteosarcoma cells that highly expressed Ezrin[1].
CAS Number
380877-02-1
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mmv667492.html
Smiles
O=C1C(NC2CCCCC2)=C(N(C)N=O)C(C3=C1C=CC=C3)=O
Molecular Formula
C17H19N3O3
Molecular Weight
313.35
References & Citations
[1]Identification of Novel Ezrin Inhibitors Targeting Metastatic Osteosarcoma by Screening Open Access Malaria Box
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported