Bucindolol

• Description :

  Bucindolol is a β1-adrenergic receptor blocker, with intrinsic sympathomimetic activity, used in the research of heart failure[1].

• UNSPSC :

  12352005

• Target :

  Adrenergic Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cardiovascular Disease; Endocrinology

• Assay Protocol :

  https://www.medchemexpress.com/bucindolol.html

• Purity :

  99.96

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  N#CC1=CC=CC=C1OCC(O)CNC(C)(C)CC2=CNC3=C2C=CC=C3

• Molecular Formula :

  C22H25N3O2

• Molecular Weight :

  363.45

• References & Citations :

  [1]Liggett SB, et al. A polymorphism within a conserved beta (1) -adrenergic receptor motif alters cardiac function and beta-blocker response in human heart failure. Proc Natl Acad Sci U S A. 2006 Jul 25;103 (30) :11288-93.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• Isoform :

  β adrenergic receptor

• CAS Number :

  [71119-11-4]