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Lucigenin

CAT: 0804-HY-D0720-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-D0720-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lucigenin is a chemiluminescence probe. Lucigenin can be used to detect the production of endogenous superoxide anion radical (O2-) . Lucigenin is extremely sensitive to chloride ions, while it combined with chloride ions, the fluorescence will be quenched. Lucigenin also can be used as a chloride indicator. Ex/Em=455/505 nm[1].
CAS Number
2315-97-1
Product Name Alternative
NSC-151912; L-6868
UNSPSC
12171500
Hazard Statement
H272, H315, H319
Target
Fluorescent Dye; Reactive Oxygen Species (ROS)
Type
Dye Reagents
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Lucigenin.html
Purity
99.12
Solubility
DMSO : 58.33 mg/mL (ultrasonic)
Smiles
C[N+]1=C2C=CC=CC2=C(C3=C4C=CC=CC4=[N+](C)C5=C3C=CC=C5)C6=C1C=CC=C6.O=N([O-])=O.O=N([O-])=O
Molecular Formula
C28H22N4O6
Molecular Weight
510.50
Precautions
H272, H315, H319
References & Citations
[1]Li Y, et al. Validation of lucigenin (bis-N-methylacridinium) as a chemilumigenic probe for detecting superoxide anion radical production by enzymatic and cellular systems. J Biol Chem. 1998 Jan 23;273 (4) :2015-23.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported