GMP Biotinylated Human DLL4 Protein, His,Avitag™

GMP Biotinylated Human DLL4 Protein, His,Avitag™

• Background: Delta-like protein 4 (DLL4) is also known as Drosophila Delta homolog 4 (Delta4), which contains one DSL domain and eight EGF-like domains. DLL4 is expressed in vascular endothelium. DLL4 is involved in the Notch signaling pathway as Notch ligand, which can activates NOTCH1 and NOTCH4. DLL4 is involved in angiogenesis and negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. DLL4 can bind to Notch-1 and Notch-4.
• Description: GMP Biotinylated Human DLL4 Protein, His,Avitag (GMP-DL4H23) is expressed from human 293 cells (HEK293). It contains AA Ser 27 - Pro 524 (Accession # NP_061947.1).
• Specifications: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 57.9 kDa. The protein migrates as 61 kDa±3 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expression Region: Ser 27 - Pro 524
• Host: HEK 293
• Target: DLL4
• Conjugation: Biotin-labeled
• Tag: C-10×His & C-Avi
• Source: Human
• Stability: -20°C to -70°C for 5 years in lyophilized state; -70°C for 12 months under sterile conditions after reconstitution._x000D_ Upon receipt, store it immediately at -20°C or lower for long term storage.
• Endotoxin: 10 EU/mg
• Purity: 95%
• Format: Powder-GMP
• Buffer: PBS, pH7.4
• Molecular Weight: 57.9 kDa
• Shipping Conditions: Blue ice
• Storage Conditions: -20°C