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Methionylserine

CAT: 0804-HY-W012159Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-W012159Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Methionylserine (H-MET-SER-OH) is a methionine- and serine-containing dipeptide. Methionylserine binds to and translocation via intestinal di/tri-peptide transporter 1 (hPEPT1) with a Km value of 0.2 mM. Methionylserine inhibits ACE enzyme activity. Methionylserine can be used in the research of hypension[1][2].
CAS Number
14517-43-2
Product Name Alternative
H-MET-SER-OH
UNSPSC
12352209
Hazard Statement
H302-H312-H332
Target
Angiotensin-converting Enzyme (ACE)
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/methionylserine.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](N)CCSC)N[C@H](C(O)=O)CO
Molecular Formula
C8H16N2O4S
Molecular Weight
236.29
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Diana Højmark Omkvist, et al. Affinity and translocation relationships via hPEPT1 of H-X aa-Ser-OH dipeptides: evaluation of H-Phe-Ser-OH as a pro-moiety for ibuprofen and benzoic acid prodrugs. Eur J Pharm Biopharm. 2011 Feb;77 (2) :327-31. |[2]Pan Wuguang, et al. Application of sulfur dipeptide for preparing antihypertensive drug or health care product. Patent WO2019006954.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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