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Human TGF-α Protein

CAT: 0749-PRP1024-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0749-PRP1024-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TGF-α is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-α is a well-characterized mammalian growth factor that might contribute to the development of Cleft lip and palate (CL/P) .
Description
Human TGF-α protein, expressed in E. coli
Product Name Alternative
ETGF; TGF-alpha; TGF type 1; TGFA
Gene ID
7039
Accession Number
P01135
Tag
TGF-α
Type
Cytokines and proteins
Applications
No tag
Purity
≥ 98 % as determined by SDS-PAGE
Activity
Testing in progress
Molecular Weight
5.5 kDa
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Features & Benefits
Endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Lyophilized Human TGF-α proteinshould be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.
Protein Length
The recombinant human TGF-α consists of 50 amino acids and has a predicted molecular mass of 5.5 kDa. The apparent molecular mass of the human TGF-α protein is approximately 5.5 kDa in SDS-PAGE under reducing conditions .
Formulation
Lyophilized from sterile 20 mM Tris, 50 mM NaCl pH 6.5.
Applications Notes
Human
Other Product Names
TGF-α, TGF α
Recommended Usage
Always centrifuge tubes before opening . It is recommended to centrifuge at 12000 rpm for 1 minute. Then reconstitute the lyophilized Human TGF-alpha protein with the buffer we provided not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Preparation
E. coli
Accession Number URL
https://www.uniprot.org/uniprot/P01135
AA Sequence
Amino acid sequence derived from Human TGF-α isoform (P01135) (Val40-Ala89) was expressed.

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