CYY292

CAT: 0804-HY-162153-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-162153-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

CYY292 is an FGFR1 inhibitor that specifically targets the FGFR1/AKT/Snail pathway in GBM cells. CYY292 dose-dependently inhibits cancer cell proliferation, epithelial-mesenchymal transition, stemness, invasion, and migration in vitro[1].

CAS Number

2644673-04-9

UNSPSC

12352005

Target

FGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cyy292.html

Purity

99.19

Solubility

10 mM in DMSO

Smiles

CN1CCN(C2=C(OC)C=C(NC3=NC(NC4=CC(NN=C5)=C5C=C4)=C(C)C=N3)C=C2)CC1

Molecular Formula

C24H28N8O

Molecular Weight

444.53

References & Citations

[1]Bi Y, et al. A novel FGFR1 inhibitor CYY292 suppresses tumor progression, invasion, and metastasis of glioblastoma by inhibiting the Akt/GSK3β/snail signaling axis. Genes Dis. 2023 Apr 3;11 (1) :479-494.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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BA8934-25	CYY292

CYY292

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