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Soraprazan

CAT: 0804-HY-100414-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-100414-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Soraprazan (BYK61359) is a selective, reversible K-competitive inhibitor of the H, K-ATPase (Ki=6.4 nM), with an IC50 of 0.19 μM in gastric glands. Soraprazan binds to the H, K-ATPase with a Kd of 28.27 nM. Soraprazan shows immediate inhibition of acid secretion and is more than 2000-fold selective for H, K-ATPase over Na, K- and Ca-ATPases[1].
CAS Number
261944-46-1
Product Name Alternative
BYK61359
UNSPSC
12352005
Target
Proton Pump
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Soraprazan.html
Purity
99.78
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O[C@@H]1[C@@H](C2=CC=CC=C2)NC3=C(C=CN4C3=NC(C)=C4C)[C@H]1OCCOC
Molecular Formula
C21H25N3O3
Molecular Weight
367.44
References & Citations
[1]Simon WA, et al. Soraprazan: setting new standards in inhibition of gastric acid secretion. J Pharmacol Exp Ther. 2007 Jun;321 (3) :866-74. Epub 2007 Mar 16.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

Alternative Products

CatalogName
M33128-01Soraprazan
A20520-25Soraprazan 25mg
A20520-100Soraprazan 100mg
A20520-50Soraprazan 50mg
A20520-5Soraprazan 5mg
A20520-10Soraprazan 10mg
A20520-1Soraprazan 1mg
A20520-10mM-DSoraprazan 10mM * 1mL in DMSO

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