P21 Polyclonal Antibody

• Background:

  CDKN1A encodes a potent cyclin-dependent kinase inhibitor. Cyclin dependent kinase inhibitor 1A binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or -cyclin-dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of CDKN1A is tightly controlled by the tumor suppressor protein p53, through which cyclin dependent kinase inhibitor 1A

• Description:

  Rabbit Anti-p21 Polyclonal Antibody

• Product Name Alternative:

  CDKN1A; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21

• Gene ID:

  1026

• Accession Number:

  P38936

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthesized peptide derived from human p21 around the non-phosphorylation site of T145

• Clonality:

  Polyclonal

• Tag:

  Cyclin-dependent kinase inhibitor 1

• Applications:

  IF, WB, IHC, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  21kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  P21 Polyclonal Antibody detects endogenous levels of p21 protein.

• Formulation:

  Liquid solution

• Buffer pH:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:50-200; WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications

• Other Product Names:

  CDKN1A; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/P38936

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG