Haptoglobin Mouse Monoclonal Antibody [5-D3]
CAT:
992-M1510-37
Size:
100 µL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
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Haptoglobin Mouse Monoclonal Antibody [5-D3]
- Description: As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.
- Product Name Alternative: Binding peptide antibody BP antibody Haptoglobin alpha chain antibody Haptoglobin alpha (1S) beta antibody Haptoglobin alpha (2FS) beta antibody Haptoglobin beta chain antibody Haptoglobin, alpha polypeptide antibody Haptoglobin, beta polypeptide antibody HP antibody HP2 ALPHA2 antibody HP2ALPHA2 antibody HPA1S antibody HPT antibody HPT_HUMAN antibody MGC111141 antibody Zonulin antibody
- Abbreviation: HP
- CAS Number: 9007-83-4
- Swiss Prot: P00738 Human
- Cellular Locus: Extracellular region, secreted.
- Host: Mouse
- Species Reactivity: Human, Mouse, Rat
- Immunogen: Native Human Haptoglobin protein.
- Isotype: IgG1
- Conjugation: Non-conjugated
- Type: Mouse monoclonal Antibody
- Applications: WB, IHC-P, IF-Cell
- Positive Control: Human lung tissue lysate, human liver tissue lysate, HepG2, Hela, rat liver tissue, mouse liver tissue, human liver tissue, human lung cancer tissue.
- Concentration: 2 mg/mL
- Dilution: WB: 1:500-1:2,000;IF-Cell: 1:100-1:500;IHC-P: 1:50-1:200
- Purity: Protein A affinity purified.
- Form: Liquid
- Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- Molecular Weight: Predicted band size: 45 kDa
- Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Recombinant Antibody: No