iFluor™ 488 Conjugated Cytokeratin 9 Recombinant Rabbit Monoclonal Antibody [SD201-09]

iFluor™ 488 Conjugated Cytokeratin 9 Recombinant Rabbit Monoclonal Antibody [SD201-09]

• Description: Cytokeratins comprise a diverse group of intermediate filament proteins that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratin 9 is an unusually large, type I acidic cytokeratin that differentiates human plantar and palmar epidermal cells. Cytokeratin 9 localizes to the suprabasal layers as well as the upper epidermal layers such as the glandular ridges and interridges. The domains of cytokeratin 9 include a head, an α-helical coiled-coil-forming rod, and a tail; cytokeratin 9 shares significant homology with cytokeratin 10. Mutations in the cytokeratin 9 gene correlate with the development of epidermolytic palmoplantar keratoderma (EPPK), an autosomal dominant inherited skin disorder that is characterized by hyperkeratosis of the skin over the palms and soles.
• Product Name Alternative: CK 9 antibody CK9 antibody CK-9 antibody Cytokeratin 9 antibody Cytokeratin-9 antibody Cytokeratin9 antibody EPPK antibody K1C9_HUMAN antibody K9 antibody Keratin 9 antibody Keratin antibody Keratin type I cytoskeletal 9 antibody Keratin-9 antibody Keratin9 antibody KRT 9 antibody Krt9 antibody Spermatid Perinuclear Ring Manchette Protein K9 antibody type I cytoskeletal 9 antibody
• Abbreviation: CK-9, K9, KRT9
• CAS Number: 9000-83-3
• Swiss Prot: P35527 Human, Q6RHW0 Mouse
• Cellular Locus: Extracellular exosome, membrane, nucleus.
• Host: Rabbit
• Species Reactivity: Human, Mouse
• Immunogen: Recombinant protein wiehin Human Cytokeratin 9 aa 234-422 / 623.
• Isotype: IgG
• Conjugation: iFluor™ 488
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: IF-Tissue
• Positive Control: Rat skin tissue.
• Concentration: 1 mg/mL
• Dilution: IF-Tissue: 1:200
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS.
• Molecular Weight: Predicted band size: 62 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes