iFluor™ 488 Conjugated Cytokeratin 7 Recombinant Rabbit Monoclonal Antibody [ST50-05]

iFluor™ 488 Conjugated Cytokeratin 7 Recombinant Rabbit Monoclonal Antibody [ST50-05]

• Description: Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue, where they constitute up to 85% of mature keratinocytes in the vertebrate epidermis. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. The a-helical coiled-coil dimers associate laterally end-to-end to form 10 nm diameter filaments. Cytokeratins are useful markers of tissue differentiation and, in addition, they aid in the characterization of malignant tumors. Cytokeratin 7 (also known as sarcolectin) agglutinates normal and transformed cells with a high affinity for simple sugars. Cytokeratin 7 also inhibits the synthesis of interferon-dependent secondary proteins thus reversing the antiviral effect of interferon induction and restoring cells to their status ad primum. In normal and transformed cells, Cytokeratin 7 localizes to the membrane.
• Product Name Alternative: CK 7 antibody CK-7 antibody CK7 antibody Cytokeratin 7 antibody Cytokeratin-7 antibody D15Wsu77e antibody K2C7 antibody K2C7_HUMAN antibody K7 antibody Keratin 7 antibody Keratin 7, type II antibody Keratin type II cytoskeletal 7 antibody Keratin, 55K type II cytoskeletal antibody Keratin, simple epithelial antibody Keratin, simple epithelial type I, K7 antibody Keratin, type II cytoskeletal 7 antibody Keratin-7 antibody Krt2-7 antibody KRT7 antibody MGC11625 antibody MGC129731 antibody MGC3625 antibody Sarcolectin antibody SCL antibody Type II mesothelial keratin K7 antibody Type-II keratin Kb7 antibody Cytokeratin7
• Abbreviation: CK-7, K7, KRT7, SCL
• CAS Number: 9000-83-3
• Swiss Prot: P08729 Human
• Cellular Locus: Cytoplasm.
• Host: Rabbit
• Species Reactivity: Human, Mouse
• Immunogen: Synthetic peptide within Human Cytokeratin 7 aa 18-67.
• Isotype: IgG
• Conjugation: iFluor™ 488
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: IF-Tissue, IF-Cell, FC
• Positive Control: Human liver tissue, A431, human breast tissue, SK-Br-3.
• Concentration: 1 mg/mL
• Dilution: IF-Tissue: 1:200;IF-Cell: 1:100;FC: 1:500-1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS.
• Molecular Weight: Predicted band size: 51 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes