iFluor™ 594 Conjugated Cytokeratin 15 Recombinant Rabbit Monoclonal Antibody [ST04-85]

iFluor™ 594 Conjugated Cytokeratin 15 Recombinant Rabbit Monoclonal Antibody [ST04-85]

• Description: Cytokeratin 15 (CK15, K15, K1CO, keratin15, type I cytoskeletal 15) is an intermediate filament (IF) type I protein that is responsible for the mechanical integrity of epithelial cells. Keratin family members are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains, and are clustered in a region on chromosome 17q21.2. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceus. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins.
• Product Name Alternative: AI528832 antibody CK 15 antibody CK-15 antibody CK15 antibody Cytokeratin-15 antibody Cytokeratin15 antibody K15 antibody K1C15_HUMAN antibody K1CO antibody Ka15 antibody Keratin 15 antibody Keratin 15 basic antibody Keratin 15 beta antibody Keratin antibody Keratin complex 1 acidic gene 15 antibody Keratin type I cytoskeletal 15 antibody Keratin-15 antibody Keratin15 antibody KRT 15 antibody Krt1-15 antibody KRT15 antibody KRTB antibody KRTL15 antibody Type I cytoskeletal 15 antibody Type I keratin Ka15 antibody
• Abbreviation: CK-15, K15, KRT15
• CAS Number: 9000-83-3
• Swiss Prot: P19012 Human, Q61414 Mouse, Q6IFV3 Rat
• Cellular Locus: Intermediate filament, cytosol, extracellular exosome, nucleus.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human Cytokeratin 15 aa 410-455.
• Isotype: IgG
• Conjugation: iFluor™ 594
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: IF-Tissue
• Positive Control: Human skin tissue, rat skin tissue.
• Concentration: 1 mg/mL
• Dilution: IF-Tissue: 1:100-1:400
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS.
• Molecular Weight: 49 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes