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PPP2R1B Rabbit Polyclonal Antibody

CAT: 0992-HA500383Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500383Size:100 µL
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Description
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform is an enzyme that in humans is encoded by the PPP2R1B gene. This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Defects in this gene could be the cause of some lung and colon cancers. At least two transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Product Name Alternative
2AAB_HUMAN antibody beta isoform of regulatory subunit A, protein phosphatase 2 antibody PP2A A beta antibody PP2A subunit A isoform PR65-beta antibody PP2A subunit A isoform R1-beta antibody PP2A, subunit A, PR65 beta isoform antibody PP2A, subunit A, R1 beta isoform antibody PPP2R1B antibody PPP4R1 antibody PR65B antibody protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform antibody protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform antibody Protein phosphatase 2, regulatory subunit A, beta antibody Protein phosphatase 2, structural/regulatory subunit A, beta antibody protein phosphatase 2, structural/regulatory subunit A, beta isoform antibody serine/threonine protein phosphatase 2A 65 kDa regulatory subunit A, beta isoform antibody serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, beta isoform antibody Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform antibody
Abbreviation
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform PP2A subunit A isoform PR65-beta PP2A subunit A isoform R1-beta PPP2R1B
Swiss Prot
P30154 Human, Q7TNP2 Mouse, Q4QQT4 Rat
Cellular Locus
Secreted, Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within human PPP2R1B aa 100-350.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, IF-Cell
Positive Control
Jurkat cell lysate, Hela cell lysate, RAW264.7 cell lysate, 293 cell lysate, rat brain liver tissue lysate, rat liver tissue lysate, mouse brain tissue lysate, human pancreas tissue, SiHa.
Concentration
2.4 mg/mL
Dilution
WB: 1:2,000 ;IHC-P: 1:600 ;IF-Cell: 1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 66 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No