IL22 RA2 Rabbit Polyclonal Antibody

This gene encodes a member of the class II cytokine receptor family. The encoded soluble protein specifically binds to and inhibits interleukin 22 activity by blocking the interaction of interleukin 22 with its cell surface receptor. The encoded protein may be important in the regulation of inflammatory response, and has been implicated in the regulation of tumorigenesis in the colon. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses. Isoform 1 may play a role in establishing and maintaining successful pregnancy. Expressed in placenta, spleen, breast, skin and lung. Also detected in intestinal tract, testis, brain, heart and thymus. No expression found in prostate, bladder, kidney, ovary, muscle, bone marrow, liver and uterus. Isoform 1 is expressed only in placenta. Isoform 2 is expressed in placenta and breast and at lower level in spleen, skin, thymus and stomach.

9007-83-4

IL 22BP antibody IL 22RA2 antibody IL22RA2 antibody Class II cytokine receptor antibody CRF2 10 antibody CRF2 S1 antibody CRF2-10 antibody CRF2-S1 antibody CRF2X antibody Cytokine receptor class II member 10 antibody Cytokine receptor class-II member 10 antibody Cytokine receptor family 2 member 10 antibody Cytokine receptor family type 2 antibody Cytokine receptor family type 2 soluble 1 antibody I22R2_HUMAN antibody IL 22 receptor subunit alpha 2 antibody IL 22R alpha 2 antibody IL-22 receptor subunit alpha-2 antibody IL-22BP antibody IL-22R-alpha-2 antibody IL-22RA2 antibody IL22 RA2 antibody IL22BP antibody IL22R alpha 2 antibody Il22ra2 antibody Interleukin 22 binding protein antibody Interleukin 22 Receptor alpha 2 antibody Interleukin-22 receptor subunit alpha-2 antibody Interleukin-22-binding protein antibody MGC150509 antibody MGC150510 antibody soluble 1 antibody ZcytoR16 antibody

Interleukin-22 receptor subunit alpha-2 IL-22 receptor subunit alpha-2 IL-22R-alpha-2 IL-22RA2 Cytokine receptor class-II member 10 Cytokine receptor family 2 member 10 CRF2-10 Cytokine receptor family type 2, soluble 1 CRF2-S1 Interleukin-22-binding protein IL-22BP IL22BP ZcytoR16 IL22RA2 UNQ5793 PRO19598 PRO19822

Q969J5 Human, Q80XF5 Mouse

Secreted

Synthetic peptide within human IL22 RA2 aa 22-71.

Non-conjugated

Rabbit polyclonal Antibody

WB, IHC-P, IF-Cell

Mouse lung tissue lysate, human lung tissue lysate, human kidney tissue, SiHa.

1.6 mg/mL

WB: 1:1,000;IHC-P: 1:200;IF-Cell: 1:200

Immunogen affinity purified.

Liquid

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Predicted band size: 30 kDa

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.