p21 ARC Rabbit Polyclonal Antibody

p21 ARC Rabbit Polyclonal Antibody

• Description: Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (. The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility . In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA . The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) .
• Product Name Alternative: Actin related protein 2/3 complex subunit 3 antibody ARC21 antibody ARP2/3 complex 21 kDa subunit antibody ARP2/3 protein complex subunit p21 antibody ARPC3 antibody
• Abbreviation: Actin-related protein 2/3 complex subunit 3 Arp2/3 complex 21 kDa subunit p21-ARC
• CAS Number: 9007-83-4
• Swiss Prot: O15145 Human, Q9JM76 Mouse
• Cellular Locus: Cell projection, Cytoplasm, Cytoskeleton, Nucleus.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within human p21 ARC aa 120-178.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IF-Cell, IHC-P
• Positive Control: HeLa cell lysate, Jurkat cell lysate, K-562 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, Mouse brain tissue lysate, Rat brain tissue lysate, rat brain tissue, human colon tissue, HUVEC.
• Concentration: 1 mg/mL
• Dilution: WB: 1:2,000 ;IHC-P: 1:50-1:200 ;IF-Cell: 1:50-1:100
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 21 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No