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p21 ARC Rabbit Polyclonal Antibody

CAT: 0992-HA500005Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500005Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (. The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility . In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA . The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) .
CAS Number
9007-83-4
Product Name Alternative
Actin related protein 2/3 complex subunit 3 antibody ARC21 antibody ARP2/3 complex 21 kDa subunit antibody ARP2/3 protein complex subunit p21 antibody ARPC3 antibody
Abbreviation
Actin-related protein 2/3 complex subunit 3 Arp2/3 complex 21 kDa subunit p21-ARC
Swiss Prot
O15145 Human, Q9JM76 Mouse
Cellular Locus
Cell projection, Cytoplasm, Cytoskeleton, Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human p21 ARC aa 120-178.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
HeLa cell lysate, Jurkat cell lysate, K-562 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, Mouse brain tissue lysate, Rat brain tissue lysate, rat brain tissue, human colon tissue, HUVEC.
Concentration
1 mg/mL
Dilution
WB: 1:2,000 ;IHC-P: 1:50-1:200 ;IF-Cell: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 21 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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