CRMP1 Recombinant Rabbit Monoclonal Antibody [JU73-30]

• Description:

  Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-1 is also involved in cancer invasion and metastasis.

• Product Name Alternative:

  Collapsin response mediator protein 1 antibody CRMP 1 antibody CRMP-1 antibody Crmp1 antibody Dihydropyrimidinase like 1 antibody Dihydropyrimidinase related protein 1 antibody Dihydropyrimidinase-related protein 1 antibody DPYL1_HUMAN antibody DPYSL1 antibody DRP 1 antibody DRP-1 antibody DRP1 antibody ULIP-3 antibody Ulip3 antibody Unc-33-like phosphoprotein 3 antibody

• Abbreviation:

  CRMP-1, ULIP-3, CRMP1, DPYSL1, ULIP3

• Swiss Prot:

  Q14194 Human, P97427 Mouse, Q62950 Rat

• Cellular Locus:

  Cytoplasm. Cytoskeleton.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide within Human CRMP1 aa 489-538 / 572.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Rabbit monoclonal Antibody

• Applications:

  WB, IF-Cell, IHC-P, FC, IP

• Positive Control:

  Human brain tissue lysate, mouse brain tissue lysate, rat brain tissue lysate, N2A, SHG-44, SH-SY5Y, rat brain tissue, mouse brain tissue, mouse cerebellum tissue.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:5,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 62 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

• Recombinant Antibody:

  Yes

• CAS Number:

  9000-83-3