DNA Ligase IV Recombinant Rabbit Monoclonal Antibody [JM64-32]

• Description:

  The X-ray repair cross-complementing protein XRCC4 and DNA Ligase IV are essential for repairing double-strand breaks in DNA. These stories form a critical complex composed of two molecules of each protein that preferentially bind DNA with nicks or broken ends. As an obligatory accessory molecule, XRCC4 binds to DNA Ligase IV and enhances its joining activity. The XRCC4 / DNA Ligase IV complex is also involved in V (D) J recombination. V (D) (in) a pair of high incidence of apoptosis in the development nervous system and a block in B and T cell maturation.

• Product Name Alternative:

  DNA ligase IV ATP dependent antibody DNA joinase antibody DNA ligase 4 antibody DNA ligase IV antibody DNA repair enzyme antibody DNLI4_HUMAN antibody LIG 4 antibody LIG4 antibody LIG4S antibody Ligase IV antibody Ligase IV DNA ATP dependent antibody Polydeoxyribonucleotide synthase [ATP] 4 antibody Polydeoxyribonucleotide synthase 4 antibody Polydeoxyribonucleotide synthase antibody Polynucleotide ligase antibody Sealase antibody

• Abbreviation:

  LIG4

• Swiss Prot:

  P49917 Human

• Cellular Locus:

  Nucleus.

• Host:

  Rabbit

• Species Reactivity:

  Human

• Immunogen:

  Recombinant protein within Human DNA Ligase IV aa 484-705 / 911.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Rabbit monoclonal Antibody

• Applications:

  WB, IHC-P, IF-Cell

• Positive Control:

  HepG2 cell lysate, Hela cell lysate, Jurkat cell lysate, human colon carcinoma tissue, human placenta tissue.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200 ;IF-Cell: 1:10-1:50

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 104 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

• Recombinant Antibody:

  Yes

• CAS Number:

  9000-83-3