Annexin A2 Recombinant Rabbit Monoclonal Antibody [JA42-30]

Annexin A2 Recombinant Rabbit Monoclonal Antibody [JA42-30]

• Description: The annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain which binds phospholipids in a Ca2+-dependent manner and a unique amino-terminal region which may confer binding specificity. The interaction between these proteins and biological membranes has led to the hypothesis that they are involved in cellular trafficking processes such as endocytosis, exocytosis and cellular adhesion. Annexin I, alternatively referred to as lipocortin, has been implicated as a mediator of the anti-inflammatory response produced by glucocorticoids and as an inhibitor of cPLA2, a potent mediator of inflammation. Annexin II, also called p36, exists as a monomer or as a heterotetramer, complexed with the S-100-related protein p11. This complex is termed calpactin I. In the tetrameric form, Annexin II is an efficient substrate of PKC family and Src pp60.
• Product Name Alternative: Annexin A2 antibody Annexin II antibody Annexin II, heavy chain antibody Annexin-2 antibody ANX 2 antibody ANX2 antibody ANX2L4 antibody ANXA2 antibody ANXA2_HUMAN antibody arylsulfatase B antibody CAL1H antibody Calpactin I heavy chain antibody calpactin I heavy polypeptide (p36) antibody Calpactin I heavy polypeptide antibody Calpactin-1 heavy chain antibody chromobindin 8 antibody Chromobindin-8 antibody Epididymis secretory protein Li 270 antibody HEL S 270 antibody LIP2 antibody Lipocortin II antibody LPC2 antibody LPC2D antibody p36 antibody P36 protein antibody PAP-IV antibody Placental anticoagulant protein IV antibody Protein I antibody
• Abbreviation: PAP-IV, ANXA2, ANX2, ANX2L4, CAL1H, LPC2D
• CAS Number: 9000-83-3
• Swiss Prot: P07355 Human, P07356 Mouse, Q07936 Rat
• Cellular Locus: Basement membrane. Melanosome.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human Annexin A2 aa 26-75 / 339.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P, IF-Cell, IF-Tissue, FC
• Positive Control: A549 cell lysate, HeLa cell lysate, K-562 cell lysate, 293T cell lysate, NIH/3T3 cell lysate, RAW264.7 cell lysate, C6 cell lysate, PC-12 cell lysate, Hela, human liver tissue, human colon carcinoma tissue, human prostate tissue, K562.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IHC-P: 1:50-1:200 ;IF-Cell:1:100-1:200 ;IF-Tissue:1:100-1:200 ;FC:1:50-1:200
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 39 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes