Cardiac Troponin I Recombinant Rabbit Monoclonal Antibody [JF0550]
CAT:
992-ET1702-37
Size:
100 µL
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
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Cardiac Troponin I Recombinant Rabbit Monoclonal Antibody [JF0550]
- Description: Actin is a highly conserved protein that is expressed in all eukaryotic cells. Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells. Myosin is a hexamer composed of two heavy chains (MHC) and four light chains (MLC); it interacts with Actin to generate the force for diverse cellular movements, including cytokinesis, phagocytosis and muscle contraction. Troponin facilitates the interaction between Actin and Myosin by binding to calcium. Troponin comprises at least two subunits, which are divergent in cardiac muscle, fast skeletal muscle and slow skeletal muscle. Structures of skeletal muscle troponin are composed of Troponin C (the sensor), Troponin I (the regulator) and Troponin T (the link to the muscle thin filament). Troponin C is dumbbell-shaped and has a hydrophobic pocket that increases the contractile force of muscle fibers. Troponin C has two isoforms: fast and slow. Fast Troponin C has two calcium binding sites while slow/cardiac Troponin C has a single calcium binding site.
- Product Name Alternative: cardiac muscle antibody Cardiac troponin I antibody cardiomyopathy, dilated 2A (autosomal recessive) antibody Cardiomyopathy, familial hypertrophic, 7, included antibody CMD1FF antibody CMD2A antibody CMH7 antibody cTnI antibody Familial hypertrophic cardiomyopathy 7 antibody MGC116817 antibody RCM1 antibody Tn1 antibody Tni antibody TNN I3 antibody TNNC 1 antibody TNNC1 antibody TNNI3 antibody TNNI3_HUMAN antibody Troponin I antibody Troponin I cardiac antibody Troponin I cardiac muscle antibody Troponin I cardiac muscle isoform antibody Troponin I type 3 cardiac antibody troponin I, cardiac 3 antibody TroponinI antibody Ttroponin I type 3 (cardiac) antibody
- Abbreviation: TNNI3
- CAS Number: 9000-83-3
- Swiss Prot: P19429 Human, P23693 Rat
- Cellular Locus: Cytosol.
- Host: Rabbit
- Species Reactivity: Human, Rat
- Immunogen: Recombinant protein within Human Cardiac Troponin I aa 1-47 / 210.
- Isotype: IgG
- Conjugation: Non-conjugated
- Type: Recombinant Rabbit monoclonal Antibody
- Applications: WB, IF-Cell, IF-Tissue, IHC-P, IP
- Positive Control: Rat heart tissue lysate, human heart tissue, HepG2.
- Concentration: 1 mg/mL
- Dilution: WB: 1:2,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:200 ;IHC-P: 1:1,000
- Purity: Protein A affinity purified.
- Form: Liquid
- Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- Molecular Weight: Predicted band size: 24 kDa
- Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Recombinant Antibody: Yes