Estrogen Related Receptor alpha Recombinant Rabbit Monoclonal Antibody [SC57-07]

Estrogen Related Receptor alpha Recombinant Rabbit Monoclonal Antibody [SC57-07]

• Description: Estrogen related receptor alpha (ERRα) is a nuclear receptor in the superfamily of ligand-regulated transcription factors and is a member of the NR3B orphan nuclear receptor subgroup (consisting of α, β and γ). ERRα plays a role in modulating the estrogen signaling pathway. In addition, the expression of ERRα has been shown to increase during fasting and cold exposure. ERRα may be important for regulating mitochondrial biogenesis and oxidative metabolism by acting directly on genes necessary for mitochondrial function. Mice lacking ERRα are unable to maintain their body temperature in the cold. ERRα may also be involved in the maintenance and formation of cartilage. This information could be useful in finding therapeutic agents for a variety of diseases affecting the joints.
• Product Name Alternative: Err 1 antibody ERR a antibody ERR alpha antibody ERR-alpha antibody Err1 antibody ERR1 protein antibody ERR1_HUMAN antibody ERRa antibody ERRalpha antibody ESRL 1 antibody ESRL1 antibody ESRR A antibody Esrra antibody Estrogen receptor like 1 antibody Estrogen receptor related 1 antibody estrogen receptor related receptor alpha antibody Estrogen receptor-like 1 antibody Estrogen related receptor alpha antibody Estrogen-related receptor alpha antibody Estrra antibody hERR1 antibody NR3B1 antibody Nuclear receptor subfamily 3 group B member 1 antibody Steroid hormone receptor ERR1 antibody
• Abbreviation: ERR-alpha, ESRRA, ERR1, ESRL1, NR3B1
• CAS Number: 9000-83-3
• Swiss Prot: P11474 Human, O08580 Mouse, Q5QJV7 Rat
• Cellular Locus: Nucleus.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human Estrogen Related Receptor alpha aa 1-49 / 423.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IP, IHC-P, IF-Tissue
• Positive Control: MCF-7 cell lysate, SK-Br-3 cell lysate, PC-3 cell lysate, human kidney tissue, mouse brain tissue, Hela.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000-1:2,000 ;FC: 1:50-1:100 ;IHC-P: 1:1,000 ;IF-Tissue: 1:200
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 46 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes