VEGF Recombinant Rabbit Monoclonal Antibody [SP07-01]

VEGF Recombinant Rabbit Monoclonal Antibody [SP07-01]

• Description: The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include fibroblast growth factors (FGFs), platelet derived growth factor (PDGF) and vascular endothelial growth factor (VEGF). VEGF is a dimeric glycoprotein with structural homology to PDGF. Several variants of VEGF have been described that arise by alternative mRNA splicing. It has been speculated that VEGF may function as a tumor angiogenesis factor in vivo because the expression pattern of VEGF is consistent with a role in embryonic angiogenesis. VEGF mRNA is formed in some primary tumors, VEGF is produced by tumor cell lines in vitro and VEGF mitogenic activity appears to be restricted to endothelial cells. A member of the PDGF receptor family, Flt, has been identified as a high-affinity receptor for VEGF.
• Product Name Alternative: Folliculostellate cell-derived growth factor antibody Glioma-derived endothelial cell mitogen antibody MGC70609 antibody MVCD1 antibody Vascular endothelial growth factor A antibody vascular endothelial growth factor A121 antibody vascular endothelial growth factor A165 antibody vascular endothelial growth factor antibody Vascular permeability factor antibody VEGF A antibody Vegf antibody VEGF-A antibody VEGF120 antibody Vegfa antibody VEGFA_HUMAN antibody VPF antibody
• Abbreviation: VEGF-A, VPF, VEGFA
• CAS Number: 9000-83-3
• Swiss Prot: P15692 Human, Q00731 Mouse, P16612 Rat
• Cellular Locus: Secreted.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human VEGF aa 183-232 / 232.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IF-Tissue, IHC-P, IP, FC
• Positive Control: Hela, MCF-7, SHG-44, SH-SY5Y, human kidney tissue, rat eyeball tissue, mouse cerebellum tissue, Hela, mouse hippocampus tissue, mouse brain tissue, NIH/3T3.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:200-1:1,000 ;FC: 1:50-1:1,000 ;IP: Use at an assay dependent concentration.
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 27 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes