Alkaline Phosphatase Recombinant Rabbit Monoclonal Antibody [SA40-00]

Alkaline Phosphatase Recombinant Rabbit Monoclonal Antibody [SA40-00]

• Description: This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects.
• Product Name Alternative: Alkaline phosphatase antibody Alkaline phosphatase placental antibody Alkaline phosphatase placental type antibody Alkaline phosphatase Regan isozyme antibody ALP antibody Alp1 antibody ALPP antibody FLJ61142 antibody Germ-cell alkaline phosphatase antibody nagao isozyme antibody OTTHUMP00000164354 antibody PALP antibody Placental alkaline phosphatase 1 antibody placental heat-stable alkaline phosphatase antibody placental type antibody PLAP antibody PLAP-1 antibody PLAP1 antibody PPB1_HUMAN antibody
• Abbreviation: AP-TNAP, TNSALP
• CAS Number: 9000-83-3
• Swiss Prot: P05186 Human, P09242 Mouse, P08289 Rat
• Cellular Locus: Cell membrane, Mitochondrion membrane, Mitochondrion intermembrane space, Extracellular vesicle membrane.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within human Alkaline Phosphatase aa 18-50.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IHC-P, IP, FC
• Positive Control: Saos-2 cell lysate, HeLa cell lysate, A549 cell lysate, mouse liver tissue lysate, rat liver tissue lysate, HepG2 cell lysate, MG-63 cell lysate, Hela, HepG2, SW480, human liver tissue, human liver carcinoma tissue, human kidney tissue, mouse kidney tissue, mouse bone tissue, rat spleen tissue lysate, rat lung tissue lysate, mouse jawbone tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:5,000 ;IF-Cell: 1:50 ;IHC-P: 1:50-1:200 ;FC: 1:50 ;IP: Use at an assay dependent concentration.
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 57 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes