[Lys5,MeLeu9,Nle10]-NKA(4-10) (TFA)

[Lys5,MeLeu9,Nle10]-NKA(4-10) (TFA)

• UNSPSC Description: [Lys5,MeLeu9,Nle10]-NKA(4-10) TFA is a highly selective and potent NK2 receptor agonist, with an IC50 of 6.1 nM[1].
• Target Antigen: Neurokinin Receptor
• Type: Peptides
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/lys5-meleu9-nle10-nka-4-10-tfa.html
• Solubility: H2O
• Smiles: OC(C(F)(F)F)=O.OC(C[C@H](N)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](C(C)C)C(NCC(N(C)[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCCC)=O)=O)=O)=O)CC1=CC=CC=C1)=O)=O)=O
• Molecular Weight: 803.99 (free base)
• References & Citations: [1]G Chassaing, et al. Selective agonists of NK-2 binding sites highly active on rat portal vein (NK-3 bioassay). Neuropeptides. 1991 Jun;19(2):91-5.|[2]M A Matuszek, et al. An investigation of tachykinin NK2 receptor subtypes in the rat. Eur J Pharmacol. 1998 Jul 3;352(1):103-9.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported