Muc1 Rabbit Polyclonal Antibody

The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.

9007-83-4

ADMCKD antibody ADMCKD1 antibody Breast carcinoma associated antigen DF3 antibody Breast carcinoma-associated antigen DF3 antibody CA 15-3 antibody CA15 3 antibody CA15 3 antigen antibody CA15-3 antibody CA15.3 antibody Cancer antigen 15-3 antibody Carcinoma associated mucin antibody Carcinoma-associated mucin antibody CD 227 antibody CD227 antibody DF3 antigen antibody EMA antibody Episialin antibody Epithelial Membrane Antigen antibody H23 antigen antibody H23AG antibody KL 6 antibody KL-6 antibody KL6 antibody Krebs von den Lungen-6 antibody MAM 6 antibody MAM6 antibody MCD antibody MCKD antibody MCKD1 antibody Medullary cystic kidney disease 1 (autosomal dominant) antibody Medullary cystic kidney disease, autosomal dominant antibody MUC 1 antibody MUC-1 antibody MUC-1/SEC antibody MUC-1/X antibody MUC1 antibody MUC1-alpha antibody MUC1-beta antibody MUC1-CT antibody MUC1-NT antibody MUC1/ZD antibody MUC1_HUMAN antibody Mucin 1 antibody Mucin 1 cell surface associated antibody Mucin 1 transmembrane antibody Mucin 1, cell surface associated antibody Mucin-1 subunit beta antibody Peanut reactive urinary mucin antibody Peanut-reactive urinary mucin antibody PEM antibody PEMT antibody Polymorphic epithelial mucin antibody PUM antibody Tumor associated epithelial membrane antigen antibody Tumor associated epithelial mucin antibody Tumor associated mucin antibody Tumor-associated epithelial membrane antigen antibody Tumor-associated mucin antibody

MUC1

P15941 Human

Plasma membrane.

Synthetic peptide immune sequence is APDTRPAPGSTAPPAHGVTSC.

Non-conjugated

Rabbit polyclonal Antibody

WB, IF-Cell, IHC-P

MCF-7 cell lysate, Hela cell lysate, MCF-7, human colon tissue, human skin tissue, human breast carcinoma tissue, human kidney tissue, human uterus tissue.

1 mg/mL

WB:1:500-1:2,000 ;IF-Cell:1:50-1:100 ;IHC-P:1:50-1:200

Immunogen affinity purified.

Liquid

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Predicted band size 122 kDa

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.