Products for Research Use Only
RegisterLogin

CD163 Rabbit Polyclonal Antibody

CAT: 0992-ER1804-03Size: 100 µLDry Ice: NoHazardous: No
Product image 1Product image 2Product image 3
1 / 3
CAT#:0992-ER1804-03Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CD163, also designated M130, is a macrophage-associated antigen that is a member of the scavenger receptor cysteine-rich (SRCR) superfamily. It is highly expressed on macrogphages and to a lesser extent on monocytes. The acute phase-regulated and signal-inducing macrophage protein, CD163, is a receptor that scavenges hemoglobin by mediating endocytosis of haptoglobin-hemoglobin complexes. CD163 binds only haptoglobin and hemoglobin in complex, which indicates the exposure of a receptor-binding neoepitope. The receptor-ligand interaction is calcium-dependent and of high affinity. The existence of several CD163 isoforms, which differ in the structure of their cytoplasmic domains and putative phosphorylation sites, suggests that these isoforms also differ in their signaling mechanism. The gene which encodes CD163 maps to human chromosome 12p13.31.
CAS Number
9007-83-4
Product Name Alternative
C163A_HUMAN antibody CD 163 antibody CD163 antibody CD163 antigen antibody CD163 molecule antibody Hemoglobin scavenger receptor antibody M130 antibody M130 antigen precursor antibody Macrophage associated antigen antibody MM130 antibody OTTHUMP00000238617 antibody OTTHUMP00000238618 antibody OTTHUMP00000238619 antibody OTTHUMP00000238620 antibody SCARI1 antibody Scavenger receptor cysteine rich type 1 protein M130 antibody sCD163 antibody Soluble CD163 antibody
Abbreviation
sCD163, CD163, M130
Swiss Prot
Q86VB7 Human, Q2VLH6 Mouse, A0A8I5ZQF0 Rat
Cellular Locus
Secreted, Cell membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human aa 22-161 / 1,156.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, IF-Cell
Positive Control
Human lung tissue lysate, human liver tissue lysate, LOVO, SH-SY5Y, Siha, A431, mouse liver tissue, rat lung tissue, human placenta tissue.
Concentration
1 mg/mL
Dilution
WB:1:500-1:1,000 ;IF-Cell:1:50-1:200 ;IHC-P:1:50-1:600
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 125 kDa, observed band size: 150 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Related Products

CatalogName
HA750412CD163 Recombinant Rabbit monoclonal Antibody
HA723706CD163 Recombinant Rabbit monoclonal Antibody
IRS002CD163 Recombinant Rabbit monoclonal Antibody
ER1901-22Anti-CD163 Antibody
ER1902-09Anti-CD163 Antibody
ER2001-15Anti-CD163 Antibody
HA723567Human CD163 Recombinant Rabbit monoclonal Antibody
HA723569Human CD163 Recombinant Rabbit monoclonal Antibody
HA723566Human CD163 Recombinant Rabbit monoclonal Antibody
HA723568BHuman CD163 Recombinant Rabbit monoclonal Antibody

Alternative Products

CatalogName
NBP2-49028Rabbit Polyclonal CD163 Antibody
MBS9466509-01CD163 Rabbit Polyclonal Antibody

Popular Products