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Kir6.2 Rabbit Polyclonal Antibody

CAT: 0992-ER1803-98Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1803-98Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow Potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive Disfect characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple Alternative spliced ​​transcript variants that encode different protein isoforms have been described for this gene.
CAS Number
9007-83-4
Product Name Alternative
ATP sensitive inward rectifier potassium channel 11 antibody Beta cell inward rectifier subunit antibody BIR antibody HHF 2 antibody HHF2 antibody IKATP antibody Inward rectifier K (+) channel Kir6.2 antibody Inwardly rectifying potassium channel KIR6.2 antibody IRK 11 antibody IRK11 antibody KCNJ11 antibody Kir 6.2 antibody Kir6.2 antibody MGC133230 antibody PHHI antibody Potassium channel inwardly rectifing subfamily J member 11 antibody Potassium channel, inwardly rectifying subfamily J member 11 antibody Potassium inwardly rectifying channel J11 antibody TNDM 3 antibody TNDM3 antibody
Abbreviation
KCNJ11
Swiss Prot
Q14654 Human, Q61743 Mouse, P70673 Rat
Cellular Locus
Membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human Kir62 aa 184-323 / 390.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, IF-Cell
Positive Control
Human liver tissue lysate, mouse liver tissue lysate, A375, PC-3M, mouse liver tissue, mouse pancreas tissue, human prostate cancer tissue.
Concentration
1 mg/mL
Dilution
WB:1:500-1:1,000 ;IF-Cell:1:50-1:200 ;IHC-P:1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 44 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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