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TRPA1 Rabbit Polyclonal Antibody

CAT: 0992-ER1803-91Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1803-91Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Receptor-activated non-selective cation channel involved in detection of pain and possibly also in cold perception and inner ear function. Has a central role in the pain response to endogenous inflammatory mediators and to a diverse array of volatile irritants, such as mustard oil, cinnamaldehyde, garlic and acrolein, an irritant from tears gas and vehicule exhaust fumes. Is also activated by menthol (in vitro). Acts also as a ionotropic cannabinoid receptor by being activated by delta9-tetrahydrocannabinol (THC), the psychoactive component of marijuana. May be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds. Probably operated by a phosphatidylinositol second messenger system.
CAS Number
9007-83-4
Product Name Alternative
ANKTM 1 antibody ANKTM1 antibody Ankyrin-like with transmembrane domains protein 1 antibody Transformation sensitive protein p120 antibody Transformation-sensitive protein p120 antibody Transient receptor potential cation channel subfamily A member 1 antibody TRPA 1 antibody Trpa1 antibody TRPA1_HUMAN antibody
Abbreviation
TRPA1, ANKTM1
Swiss Prot
O75762 Human, Q8BLA8 Mouse, Q6RI86 Rat
Cellular Locus
Cell membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human TRPA1 aa 505-755 / 1,119.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
L929 cell lysates, rat brain tissue, human skin tissue, human esophagus tissue, mouse colon tissue.
Concentration
1 mg/mL
Dilution
WB:1:500-1:1,000 ;IHC-P:1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 127 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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