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Calnexin Rabbit Polyclonal Antibody

CAT: 0992-ER1803-42Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1803-42Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Calnexin and Calregulin (also called calreticulin) are calcium-binding proteins that are localized to the endoplasmic reticulum, Calnexin to the membrane and Calregulin to the lumen. Calnexin is a type I membrane protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may play a role in assisting with protein assembly and in retaining unassembled protein subunits in the endoplasmic reticulum. Calregulin has both low- and high-affinity calcium-binding sites. Neither Calnexin nor Calregulin contains the calcium-binding “E-F hand” motif found in calmodulins. Calnexin and Calregulin are important for the maturation of glycoproteins in the endoplasmic reticulum and appear to bind many of the same proteins.
CAS Number
9007-83-4
Product Name Alternative
Calnexin antibody CALX_HUMAN antibody CANX antibody CNX antibody FLJ26570 antibody Histocompatibility complex class I antigen binding protein p88 antibody IP90 antibody Major histocompatibility complex class I antigen-binding protein p88 antibody p90 antibody
Abbreviation
CANX
Swiss Prot
P27824 Human, P35564 Mouse
Cellular Locus
Endoplasmic reticulum membrane, Endoplasmic reticulum, Melanosome.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human Calnexin aa 555-592/592.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC, IP
Positive Control
Daudi cell lysate, mouse lung tissue lysate, human kidney tissue, SKOV-3, Hela cell lysate, rat lung tissue lysate, rat brain tissue lysate, rat brain tissue, human brain tissue, mouse brain tissue.
Concentration
1 mg/mL
Dilution
WB:1:2,000- 1:10,000 ;IHC-P: 1:200-1:500 ;FC: 1:50-1:100 ;IP: 1-2μg/sample
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 68 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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